Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | PKM | P14618 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680873 | 0.87 | ALDH1A1 (0.43) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL13680875 | 0.87 | ALDH1A1 (0.46) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL13680870 | 0.86 | KIF11 (0.42) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL13680880 | 0.86 | TSHR (0.42) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL13681004 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL13680894 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL13680891 | 0.83 | PSMB8 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL13680881 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2HTTNQO2MEN1KMT2A | |
| SCHEMBL13681019 | 0.81 | ALDH1A1 (0.36) | SMN1; SMN2HTTL3MBTL1NQO2KMT2A | |
| SCHEMBL13681009 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2HTTNQO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |