Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680988 | 0.88 | MAPT (0.44) | AVPR1BMAPTTP53LMNARAB9A | |
| SCHEMBL13681038 | 0.86 | MAPT (0.41) | MAPTTP53LMNARAB9ANPC1 | |
| SCHEMBL13680932 | 0.86 | KMT2A (0.47) | MAPTTP53LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13680937 | 0.84 | KDM4E (0.52) | MAPTTP53LMNARAB9ANPC1 | |
| SCHEMBL13680945 | 0.83 | MEN1 (0.52) | AVPR1BMAPTTP53LMNARAB9A | |
| SCHEMBL19846771 | 0.83 | AVPR1B (0.51) | AVPR1BMAPTTP53LMNARAB9A | |
| SCHEMBL15349056 | 0.83 | AVPR1B (0.51) | AVPR1BMAPTTP53LMNARAB9A | |
| SCHEMBL13680951 | 0.82 | MAPT (0.55) | MAPTTP53LMNARAB9ANPC1 | |
| SCHEMBL13680958 | 0.82 | RXFP1 (0.57) | MAPTTP53LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13681039 | 0.82 | MAPT (0.43) | MAPTTP53LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |