Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.64 |
| ▸ | BRS3 | P32247 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19292508 | 0.86 | PDE10A (0.55) | PDE10ABRS3HPGDS | |
| SCHEMBL1501948 | 0.78 | PDE10A (0.70) | PDE10ABRS3NPY5RSCN2AHPGDS | |
| SCHEMBL1501842 | 0.78 | PDE10A (1.00) | PDE10ABRS3NPY5RSCN2AHPGDS | |
| SCHEMBL19292016 | 0.75 | PDE10A (0.43) | PDE10ABRS3NPY5RHPGDS | |
| SCHEMBL19292309 | 0.75 | HPGDS (0.45) | PDE10ABRS3NPY5RHPGDS | |
| SCHEMBL19292023 | 0.75 | PDE10A (0.43) | PDE10ABRS3HPGDS | |
| SCHEMBL259049 | 0.74 | PDE10A (0.64) | PDE10ANPY5RSCN2AHPGDSMASP2 | |
| SCHEMBL1501900 | 0.74 | PDE10A (0.64) | PDE10ANPY5RSCN2AHPGDSMASP2 | |
| SCHEMBL2562957 | 0.74 | PDE10A (0.64) | PDE10ANPY5RSCN2AHPGDSMASP2 | |
| SCHEMBL5282438 | 0.73 | PDE10A (0.58) | PDE10ABRS3NPY5RSCN2AHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |