Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621943 | 0.87 | ALDH1A1 (0.49) | NPC1RAB9AMEN1KMT2ADDB1 | |
| SCHEMBL136476 | 0.86 | ALDH1A1 (0.67) | NPC1RAB9AMEN1KMT2ADDB1 | |
| SCHEMBL76559 | 0.85 | ALDH1A1 (0.59) | NPC1RAB9AMEN1KMT2ADDB1 | |
| Hydrochloric Acid SCHEMBL7466356 | 0.85 | ALDH1A1 (0.65) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL329316 | 0.83 | ALDH1A1 (0.58) | NPC1RAB9AMEN1KMT2ADDB1 | |
| SCHEMBL1626841 | 0.83 | ALDH1A1 (0.58) | NPC1RAB9AMEN1KMT2ADDB1 | |
| Hydrochloric Acid SCHEMBL7459714 | 0.83 | ALDH1A1 (0.58) | NPC1RAB9AMEN1KMT2ADDB1 | |
| SCHEMBL1750928 | 0.83 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2ADDB1 | |
| SCHEMBL19962687 | 0.82 | ALDH1A1 (0.45) | NPC1RAB9AMEN1KMT2ADDB1 | |
| 2-Pyrrolidone SCHEMBL4544107 | 0.82 | CRBN (0.51) | NPC1RAB9AMEN1KMT2ADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 694 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101951914-A | Androsterone derivant and using method thereof | CALIFORNIA PACIFIC MED CT | 2011-01-19 | — | — | CN | claimed |
| US-20090105202-A1 | Androsterone Derivatives and Method of Use thereof | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2009-04-23 | — | — | US | claimed |
| WO-2008061238-A2 | PROCESSES FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-05-22 | — | — | WO | claimed |
| JP-2007520453-A | — | — | 2007-07-26 | — | — | JP | claimed |
| US-7138475-B2 | Compositions for golf equipment | ACUSHNET COMPANY (US) | 2006-11-21 | — | — | US | claimed |
| EP-1682499-A1 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | Microbia, Inc. (US) | 2006-07-26 | — | — | EP | claimed |
| WO-2005047248-A1 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2005-05-26 | — | — | WO | claimed |
| US-20040220377-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | claimed |
| EP-0751934-A1 | SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORPORATION (US) | 1997-01-08 | — | — | EP | claimed |
| WO-1995026334-A1 | SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORPORATION (US) | 1995-10-05 | — | — | WO | claimed |
| JP-10130232-A | — | — | None | — | — | JP | disclosed |
| CN-113242880-B | Tire with a tire body | 住友橡胶工业株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-115485152-B | Pneumatic radial tire for passenger car | 住友橡胶工业株式会社 | 2025-03-18 | — | — | CN | disclosed |
| CN-113752753-B | Pneumatic tire | 住友橡胶工业株式会社 | 2025-03-14 | — | — | CN | disclosed |
| CN-119403685-A | Tire with a tire body | 住友橡胶工业株式会社 | 2025-02-07 | — | — | CN | disclosed |
| EP-0438248-A2 | Preparation process of toner | NIPPON ZEON CO., LTD. (JP) | 1991-07-24 | — | — | EP | disclosed |
| US-5001196-A | Process for preparation of diene type polymer rubber | NIPPON ZEON CO., LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0388921-A2 | Additive for organic solvent or thermoplastic polymer | NIPPON ZEON CO., LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0382205-A2 | Additive for thermosetting resins and thermosetting resin composition containing additive | NIPPON ZEON CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| CN-86105247-A | Antibiotic intermediate and preparation method | — | 1987-02-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105202-A1 | Androsterone Derivatives and Method of Use thereof | HSD17B11, CYP19A1, SHBG | NPC1 844/4885RAB9A 4628/4885MEN1 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.