Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656364 | 0.79 | KCNH2 (0.33) | KCNH2CACNA1I | |
| SCHEMBL13656377 | 0.79 | KCNH2 (0.33) | KCNH2CACNA1I | |
| SCHEMBL13656334 | 0.78 | KCNH2 (0.36) | KCNH2CACNA1I | |
| SCHEMBL13683428 | 0.75 | — | — | |
| SCHEMBL14505150 | 0.75 | — | — | |
| SCHEMBL18859483 | 0.74 | ALDH1A1 (0.35) | KCNH2CACNA1I | |
| SCHEMBL13660266 | 0.74 | MCHR1 (0.38) | KCNH2CACNA1I | |
| SCHEMBL13660207 | 0.73 | GLB1 (0.47) | — | |
| SCHEMBL13472101 | 0.73 | LTA4H (0.43) | KCNH2CACNA1I | |
| SCHEMBL13660209 | 0.73 | GLB1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592373-B2 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-22 | — | — | US | disclosed |
| US-7592373-B2 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-22 | — | — | US | disclosed |