Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13684404 | 0.81 | ALDH1A1 (0.41) | TRPM8ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27440981 | 0.78 | MAPT (0.35) | MAPT | |
| SCHEMBL13686217 | 0.78 | MEN1 (0.47) | MAPTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL18170195 | 0.75 | TAS1R3 (0.34) | TRPM8ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL20899727 | 0.75 | CYP3A4 (0.31) | TRPM8TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5351163 | 0.75 | TAS1R3 (0.34) | TRPM8ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL20899800 | 0.75 | CYP3A4 (0.31) | TRPM8TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL20899955 | 0.75 | CYP3A4 (0.31) | TRPM8TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17777043 | 0.75 | ALDH1A1 (0.37) | TRPM8MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17777044 | 0.75 | ALDH1A1 (0.37) | TRPM8MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |