⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28139720 | 0.79 | SKP2 (0.37) | — | |
| SCHEMBL29164246 | 0.78 | GPR84 (0.40) | — | |
| SCHEMBL9615931 | 0.77 | LTB4R (0.33) | — | |
| SCHEMBL256012 | 0.72 | — | — | |
| SCHEMBL132218 | 0.72 | — | — | |
| SCHEMBL830068 | 0.72 | — | — | |
| SCHEMBL4689576 | 0.71 | — | — | |
| SCHEMBL25285429 | 0.70 | — | — | |
| SCHEMBL7015294 | 0.70 | — | — | |
| SCHEMBL13354355 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023108536-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023109120-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| EP-1902050-B1 | OXAZOLIDINONE DERIVATIVES AND USE THEREOF AS ANTIBIOTICS | FERRER INT (ES) | 2009-09-09 | — | — | EP | disclosed |