Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.51 |
| ▸ | CD74 | P04233 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038387 | 0.93 | CTSS (0.50) | CTSSCD74 | |
| SCHEMBL13221888 | 0.92 | CTSS (0.56) | CTSSCD74 | |
| SCHEMBL14016010 | 0.91 | CTSS (0.61) | CTSSCD74 | |
| SCHEMBL13687644 | 0.90 | CTSS (0.53) | CTSSCD74 | |
| SCHEMBL8404722 | 0.90 | CTSS (0.49) | CTSSCD74 | |
| SCHEMBL13687675 | 0.86 | CTSS (0.53) | CTSSCD74 | |
| SCHEMBL2972028 | 0.85 | CTSS (0.56) | CTSSCD74 | |
| SCHEMBL2975010 | 0.84 | CTSS (0.61) | CTSSCD74 | |
| SCHEMBL2975035 | 0.84 | CTSS (0.59) | CTSSCD74 | |
| SCHEMBL14096862 | 0.83 | CTSS (0.50) | CTSSCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589202-B2 | Substituted pyrazoles | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2009-09-15 | — | — | US | disclosed |
| US-7429591-B2 | Substituted pyrazoles | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2008-09-30 | — | — | US | disclosed |