Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.53 |
| ▸ | CD74 | P04233 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408389 | 0.96 | CTSS (0.57) | CTSSCD74 | |
| SCHEMBL14107716 | 0.91 | CTSS (0.65) | CTSSCD74 | |
| SCHEMBL13687644 | 0.88 | CTSS (0.53) | CTSSCD74 | |
| SCHEMBL13222336 | 0.87 | CTSS (0.69) | CTSSCD74 | |
| SCHEMBL13687452 | 0.86 | CTSS (0.51) | CTSSCD74 | |
| SCHEMBL2967059 | 0.84 | CTSS (0.71) | CTSSCD74 | |
| SCHEMBL14096747 | 0.83 | CTSS (0.64) | CTSSCD74 | |
| SCHEMBL14107715 | 0.82 | CTSS (0.52) | CTSSCD74 | |
| SCHEMBL14096862 | 0.81 | CTSS (0.50) | CTSSCD74 | |
| SCHEMBL14038387 | 0.80 | CTSS (0.50) | CTSSCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589202-B2 | Substituted pyrazoles | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2009-09-15 | — | — | US | disclosed |