Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770089 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4EDDB1CRBNEPHX2 | |
| SCHEMBL13689087 | 0.81 | HDAC6 (0.35) | ALDH1A1HSD11B1RAB9A | |
| SCHEMBL13688862 | 0.78 | HSD11B1 (0.41) | DDB1CRBNHSD11B1RAB9AKMT2A | |
| SCHEMBL13688860 | 0.76 | CXCR2 (0.39) | KDM4ERAB9A | |
| SCHEMBL4032772 | 0.73 | ALDH1A1 (0.67) | ALDH1A1KDM4EL3MBTL1PKMRAB9A | |
| SCHEMBL5717582 | 0.72 | ALDH1A1 (0.61) | ALDH1A1KDM4EDDB1CRBNL3MBTL1 | |
| SCHEMBL3412774 | 0.68 | DDB1 (0.40) | ALDH1A1KDM4EDDB1CRBNEPHX2 | |
| SCHEMBL1770200 | 0.68 | ALDH1A1 (0.48) | ALDH1A1KDM4EDDB1CRBNHSD11B1 | |
| SCHEMBL1769989 | 0.67 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD11B1RAB9AKMT2A | |
| SCHEMBL1770331 | 0.67 | EPHX2 (0.50) | ALDH1A1EPHX2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106817-A2 | COMPOUND | STERIX LIMITED (GB) | 2009-09-03 | — | — | WO | disclosed |