Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443626 | 0.87 | PTPN2 (0.35) | PTPN2PTPN1CDC25B | |
| SCHEMBL1535486 | 0.86 | ALDH1A1 (0.42) | PTPN2PTPN1CDC25BALDH1A1MAPT | |
| SCHEMBL3178994 | 0.85 | GLA (0.36) | GLA | |
| SCHEMBL1535496 | 0.85 | ALDH1A1 (0.49) | CDC25BALDH1A1MAPTTHRBTDP1 | |
| SCHEMBL4654368 | 0.83 | ALDH1A1 (0.51) | CDC25BALDH1A1MAPTTHRBTDP1 | |
| SCHEMBL8439720 | 0.83 | ALDH1A1 (0.51) | CDC25BALDH1A1MAPTTHRBTDP1 | |
| SCHEMBL8438882 | 0.83 | ALDH1A1 (0.51) | CDC25BALDH1A1MAPTTHRBTDP1 | |
| SCHEMBL5970520 | 0.83 | ALDH1A1 (0.51) | CDC25BALDH1A1MAPTTHRBTDP1 | |
| SCHEMBL5722122 | 0.83 | ALDH1A1 (0.51) | CDC25BALDH1A1MAPTTHRBTDP1 | |
| SCHEMBL187581 | 0.83 | ALDH1A1 (0.51) | CDC25BALDH1A1MAPTTHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108484-A1 | SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS | GE HEALTHCARE LIMITED (GB) | 2009-09-03 | — | — | WO | disclosed |