Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | PCNA | P12004 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689444 | 0.90 | MEN1 (0.54) | KMT2AMEN1MMEITGB1ITGA4 | |
| SCHEMBL13602312 | 0.82 | ITGB1 (0.47) | KMT2AMEN1ITGB1ITGA4SMN1; SMN2 | |
| SCHEMBL8278658 | 0.80 | NLRP3 (0.56) | KMT2AMEN1NLRP3SMN1; SMN2ALDH1A1 | |
| SCHEMBL13602340 | 0.73 | ITGB1 (0.48) | ITGB1ITGA4SMN1; SMN2MAPTTACR1 | |
| SCHEMBL13602308 | 0.72 | SMN1; SMN2 (0.59) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL13602310 | 0.72 | FPR2 (0.54) | KMT2AMEN1TSHRITGB1ITGA4 | |
| SCHEMBL13602309 | 0.69 | KMT2A (0.64) | KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11989410 | 0.68 | PCNA (0.61) | KDM4ECYP3A4MAPK1PCNALMNA | |
| SCHEMBL13690013 | 0.67 | ITGB1 (0.46) | ITGB1ITGA4SMN1; SMN2MAPTTACR1 | |
| SCHEMBL25596407 | 0.67 | ESR1 (0.47) | KDM4EPCNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595399-B2 | Tyrosine derivatives | GENENTECH, INC. (US) | 2009-09-29 | — | — | US | disclosed |