Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498880 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL28912017 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL31046181 | 0.85 | KMT2A (0.59) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL359218 | 0.85 | KMT2A (0.59) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL3267301 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL5438190 | 0.84 | GPR35 (0.58) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL15395529 | 0.84 | KMT2A (0.57) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| Acetic Acid SCHEMBL9323112 | 0.82 | CYP1A2 (0.57) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL1628292 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL8586329 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TSHRKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595399-B2 | Tyrosine derivatives | GENENTECH, INC. (US) | 2009-09-29 | — | — | US | disclosed |