Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.31 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4547280 | 0.95 | PIK3CG (0.39) | ABL1PI4KBPI4KAPIK3CGPIK3CD | |
| SCHEMBL10182678 | 0.90 | PIK3CG (0.37) | ABL1PI4KBPI4KAPIK3CG | |
| SCHEMBL4550901 | 0.88 | ALDH1A1 (0.35) | PI4KBPI4KAPIK3CGPIK3CDPIK3CA | |
| SCHEMBL4550836 | 0.88 | ACHE (0.35) | PI4KBPI4KAPIK3CGPIK3CDPIK3CA | |
| SCHEMBL4547347 | 0.88 | CYP3A4 (0.35) | ABL1PI4KBPIK3CGPIK3CDPIK3CA | |
| SCHEMBL10182250 | 0.88 | AURKA (0.35) | PI4KBPI4KAPIK3CGPIK3CDPIK3CA | |
| SCHEMBL4550902 | 0.87 | ALDH1A1 (0.34) | PI4KBPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL10182526 | 0.87 | AURKA (0.35) | PI4KBPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4547345 | 0.86 | AURKA (0.36) | PI4KBPI4KAPIK3CGPIK3CDPIK3CA | |
| SCHEMBL4547235 | 0.86 | PIK3CG (0.39) | PIK3CGPIK3CDPIK3CAPIK3CBAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009112565-A1 | THIAZOLYL-DIHYDRO-INDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-17 | — | — | WO | disclosed |