Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16361913 | 0.99 | MEN1 (0.43) | MEN1KMT2ASUMO2SUMO1SENP7 | |
| SCHEMBL18293533 | 0.86 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPK1CASP6 | |
| SCHEMBL135180 | 0.82 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL9815014 | 0.82 | MEN1 (0.55) | MEN1KMT2ASUMO2SUMO1SENP7 | |
| SCHEMBL12146309 | 0.81 | MEN1 (0.54) | MEN1KMT2AALDH1A1SNCAKDM4E | |
| SCHEMBL1369158 | 0.81 | DUSP5 (0.42) | MEN1KMT2AALDH1A1MAPK1HSD17B10 | |
| SCHEMBL4296859 | 0.80 | MEN1 (0.56) | MEN1KMT2ASUMO2SUMO1SENP7 | |
| SCHEMBL28948590 | 0.79 | MEN1 (0.55) | MEN1KMT2ASUMO2SUMO1SENP7 | |
| SCHEMBL136734 | 0.79 | MEN1 (0.44) | MEN1KMT2ASUMO2SUMO1SENP7 | |
| SCHEMBL14695213 | 0.78 | MEN1 (0.43) | MEN1KMT2AALDH1A1CASP6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916137-B2 | Monofunctional carbocyanine dyes for in vivo and in vitro imaging | THE GENERAL HOSPITAL CORPORATION (US) | 2014-12-23 | — | — | US | disclosed |
| US-20110286933-A1 | MONOFUNCTIONAL CARBOCYANINE DYES FOR IN VIVO AND IN VITRO IMAGING | THE GENERAL HOSPITAL CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| WO-2010054330-A2 | MONOFUNCTIONAL CARBOCYANINE DYES FOR IN VIVO AND IN VITRO IMAGING | THE GENERAL HOSPITAL CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110286933-A1 | MONOFUNCTIONAL CARBOCYANINE DYES FOR IN VIVO AND IN VITRO IMAGING | MKI67, HCCS, PYCR1 | MEN1 448/4885KMT2A 2709/4885SUMO2 2724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.