Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CASP6 | P55212 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.30 |
| ▸ | NSD2 | O96028 | 2/20 | 0.30 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.30 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14695213 | 0.99 | MEN1 (0.43) | MEN1KMT2AFOLH1ALDH1A1HSD17B10 | |
| SCHEMBL14299277 | 0.88 | MEN1 (0.46) | MEN1KMT2AALDH1A1HSD17B10CASP6 | |
| SCHEMBL101662 | 0.86 | MEN1 (0.38) | MEN1KMT2AFOLH1ALDH1A1CYP2C9 | |
| SCHEMBL178269 | 0.84 | CYP2D6 (0.39) | MEN1KMT2ACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL29331376 | 0.84 | FOLH1 (0.32) | FOLH1ALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL101351 | 0.83 | CYP2D6 (0.38) | MEN1KMT2A | |
| SCHEMBL4296859 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1HSD17B10CASP6 | |
| SCHEMBL14566372 | 0.82 | MEN1 (0.55) | MEN1KMT2AALDH1A1HSD17B10POLB | |
| Potassium Ion SCHEMBL14695214 | 0.82 | MEN1 (0.43) | MEN1KMT2ATDP1 | |
| SCHEMBL135180 | 0.81 | MEN1 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240249-A1 | CYANINE DERIVATIVES AND RELATED USES | ELEMENT BIOSCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20230159547-A1 | COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME | FUJIFILM CORPORATION (JP) | 2023-05-25 | — | — | US | disclosed |
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| WO-2022129336-A1 | PH RESPONSIVE CYANINE DYES AND CONJUGATES THEREOF | BRACCO IMAGING SPA (IT) | 2022-06-23 | — | — | WO | disclosed |
| US-20220178921-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | VISEN MEDICAL, INC. | 2022-06-09 | — | — | US | disclosed |
| US-11193932-B2 | 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof | VISEN MEDICAL, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-20200049709-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | VISEN MEDICAL, INC. | 2020-02-13 | — | — | US | disclosed |
| US-10473658-B2 | 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof | VISEN MEDICAL, INC. (US) | 2019-11-12 | — | — | US | disclosed |
| US-10442930-B2 | Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels | VISEN MEDICAL, INC. (US) | 2019-10-15 | — | — | US | disclosed |
| US-20120052507-A1 | PHOSPHOLINKED DYE ANALOGS WITH AN AMINO ACID LINKER | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012027618-A2 | FUNCTIONALIZED CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012027623-A2 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
| US-6734310-B2 | A CYANINE DYE, WITH A COMBINATION OF SULPHOARYL GROUPS, ALKYL SUBSTITUENTS IN THE MESO POSITION OF THE METHINE CHAIN AND AT LEAST ONE REACTIVE GROUP WHICH PERMITS BINDING TO BIOMOLECULES. | FEW CHEMICALS GMBH (DE) | 2004-05-11 | — | — | US | disclosed |
| EP-1394219-A1 | PH sensitive cyanine dyes as reactive fluorescent reagents | CARNEGIE-MELLON UNIVERSITY (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1272566-B1 | FLUORESCENT MARKER | FEW CHEMICALS GMBH (DE) | 2003-12-17 | — | — | EP | disclosed |
| US-20030135058-A1 | Flurescent marker | FEW CHEMICALS GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
| EP-1212375-A2 | PH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS | CARNEGIE-MELLON UNIVERSITY (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2000075237-A2 | pH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS | CARNEGIE MELLON UNIVERSITY (US) | 2000-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159547-A1 | COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME | CD209, MRPL9, RXFP1 | MEN1 773/4885KMT2A 2297/4885FOLH1 1632/4885 |
| US-20120052507-A1 | PHOSPHOLINKED DYE ANALOGS WITH AN AMINO ACID LINKER | CHAMP1, MTAP, INCENP | MEN1 1891/4885KMT2A 491/4885FOLH1 614/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | MEN1 2288/4885KMT2A 2564/4885FOLH1 1820/4885 |
| US-20200049709-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | CPNE4, LIG4, S100A4 | MEN1 1137/4885KMT2A 2049/4885FOLH1 831/4885 |
| US-20220178921-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | CPNE4, LIG4, S100A4 | MEN1 1137/4885KMT2A 2049/4885FOLH1 831/4885 |
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | MEN1 2288/4885KMT2A 2564/4885FOLH1 1820/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | MEN1 2288/4885KMT2A 2564/4885FOLH1 1820/4885 |
| US-20030135058-A1 | Flurescent marker | MYADM, CCL2, CD14 | MEN1 1576/4885KMT2A 2284/4885FOLH1 1182/4885 |
| US-10473658-B2 | 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof | CPNE4, LIG4, S100A4 | MEN1 1137/4885KMT2A 2049/4885FOLH1 831/4885 |
| US-11193932-B2 | 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof | CPNE4, LIG4, S100A4 | MEN1 1137/4885KMT2A 2049/4885FOLH1 831/4885 |
| US-10442930-B2 | Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels | DNPEP, FUT5, NES | MEN1 1657/4885KMT2A 2800/4885FOLH1 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.