Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 17/20 | 0.64 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343923 | 0.89 | CCR9 (0.76) | CCR9CCR2 | |
| SCHEMBL343780 | 0.86 | CCR9 (0.78) | CCR9CCR2KDM1A | |
| SCHEMBL2532893 | 0.81 | ALDH1A1 (0.65) | CCR9CCR2KDM1AMETAP2SLC10A6 | |
| SCHEMBL12474674 | 0.79 | CCR9 (0.63) | CCR9CCR2 | |
| SCHEMBL16574547 | 0.79 | CCR9 (0.61) | CCR9KDM1AMETAP2 | |
| SCHEMBL344413 | 0.78 | CCR9 (1.00) | CCR9METAP2SLC10A6 | |
| SCHEMBL4649665 | 0.78 | METAP2 (0.74) | CCR9CCR2KDM1AMETAP2SLC10A6 | |
| SCHEMBL344369 | 0.77 | CCR9 (0.79) | CCR9CCR2 | |
| SCHEMBL15777341 | 0.77 | CCR9 (0.78) | CCR9CCR2 | |
| SCHEMBL343042 | 0.77 | CCR9 (0.78) | CCR9CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582661-B2 | Aryl sulfonamides | CHEMOCENTRYX, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-7582661-B2 | Aryl sulfonamides | CHEMOCENTRYX, INC. (US) | 2009-09-01 | — | — | US | disclosed |