Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830033 | 0.93 | F10 (0.48) | F10KLKB1 | |
| SCHEMBL8445059 | 0.91 | F10 (0.49) | F10KLKB1FPR2TYK2 | |
| SCHEMBL13694695 | 0.89 | F10 (0.49) | F10FPR2 | |
| SCHEMBL3835295 | 0.87 | F10 (0.50) | F10KLKB1 | |
| SCHEMBL3829963 | 0.84 | F10 (0.58) | F10 | |
| SCHEMBL14138847 | 0.84 | F10 (0.54) | F10FPR2ATML3MBTL1 | |
| SCHEMBL3833444 | 0.83 | F10 (0.56) | F10KLKB1 | |
| SCHEMBL3835819 | 0.82 | F10 (0.55) | F10KLKB1 | |
| SCHEMBL3835365 | 0.81 | F10 (0.57) | F10KLKB1 | |
| SCHEMBL3836042 | 0.79 | F10 (0.63) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221546-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | PFIZER INC | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221546-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | F11, F2, TFPI | F10 10/4885KLKB1 110/4885FPR2 2682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.