Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833444 | 0.92 | F10 (0.56) | F10KLKB1KCNH2 | |
| SCHEMBL3835819 | 0.91 | F10 (0.55) | F10KLKB1KCNH2 | |
| SCHEMBL13694708 | 0.91 | F10 (0.42) | F10KLKB1TYK2FPR2 | |
| SCHEMBL3835365 | 0.90 | F10 (0.57) | F10KLKB1KCNH2 | |
| SCHEMBL3834815 | 0.87 | F10 (0.58) | F10KLKB1KCNH2 | |
| SCHEMBL14039714 | 0.85 | F10 (0.59) | F10KLKB1KCNH2 | |
| SCHEMBL3835295 | 0.84 | F10 (0.50) | F10KLKB1KCNH2 | |
| SCHEMBL3828769 | 0.84 | F10 (0.51) | F10TYK2FPR2 | |
| SCHEMBL3836109 | 0.83 | F10 (0.70) | F10KLKB1 | |
| SCHEMBL3832154 | 0.83 | F10 (0.70) | F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407974-B2 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | PFIZER INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20050250815-A1 | Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade | WARNER-LAMBERT COMPANY LLC | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250815-A1 | Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade | F12, TFPI, F11 | F10 9/4885KLKB1 120/4885TYK2 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.