Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.49 |
| ▸ | MET | P08581 | 4/20 | 0.49 |
| ▸ | SYK | P43405 | 6/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1040153 | 0.90 | ALK (0.63) | BTKALKMETEGFRPTK2 | |
| SCHEMBL13695177 | 0.90 | SYK (0.61) | SYK | |
| SCHEMBL13695297 | 0.87 | SYK (0.53) | BTKALKMETSYKEGFR | |
| SCHEMBL12765469 | 0.80 | GLO1 (0.60) | ALKMETSYKEGFR | |
| SCHEMBL1040131 | 0.79 | ALK (0.64) | ALKMETEGFRPTK2 | |
| SCHEMBL12765495 | 0.78 | ALK (0.68) | ALKMETEGFRCTSCPTK2 | |
| Hydrochloric Acid SCHEMBL1035670 | 0.77 | ALK (0.67) | ALKMETEGFRCTSCPTK2 | |
| SCHEMBL13695322 | 0.77 | SYK (0.64) | SYK | |
| SCHEMBL12765459 | 0.77 | ALK (0.67) | BTKALKMETSYKEGFR | |
| SCHEMBL13695178 | 0.76 | SYK (0.65) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009112490-A1 | SULFONAMIDES AS ZAP-70 INHIBITORS | CELLZOME LIMITED (GB) | 2009-09-17 | — | — | WO | disclosed |