Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265857 | 0.85 | L3MBTL1 (0.47) | L3MBTL1F10F2PRSS1MTNR1A | |
| Hydrochloric Acid SCHEMBL5425827 | 0.84 | L3MBTL1 (0.46) | L3MBTL1F10F2PRSS1MTNR1A | |
| SCHEMBL21609290 | 0.84 | F10 (0.49) | F10F2PRSS1ALDH1A1TSHR | |
| SCHEMBL13724830 | 0.84 | L3MBTL1 (0.55) | L3MBTL1MTNR1AMTNR1BMAPK1ALDH1A1 | |
| SCHEMBL21631926 | 0.83 | GABBR2 (0.61) | L3MBTL1MTNR1AMTNR1BTSHRAOC3 | |
| SCHEMBL21656590 | 0.83 | L3MBTL1 (0.51) | L3MBTL1MTNR1AMTNR1BMAPK1ROCK2 | |
| SCHEMBL21609295 | 0.83 | F10 (0.48) | L3MBTL1F10F2PRSS1MAPK1 | |
| SCHEMBL29847219 | 0.83 | F10 (0.48) | L3MBTL1F10F2PRSS1MAPK1 | |
| SCHEMBL563435 | 0.83 | F10 (0.48) | F10F2PRSS1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7189616 | 0.83 | L3MBTL1 (0.53) | L3MBTL1MTNR1AMTNR1BMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461329-B2 | Isoquinoline derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20110288293-A1 | ISOQUINOLINE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-2377851-A1 | ISOQUINOLINE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288293-A1 | ISOQUINOLINE DERIVATIVE | HRH1, HRH2, HRH4 | L3MBTL1 4825/4885F10 4394/4885F2 4168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.