Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070028 | 0.87 | HIF1A (0.75) | CYP3A4ALOX15HIF1APTGS1KMT2A | |
| SCHEMBL5025012 | 0.87 | HIF1A (0.75) | CYP3A4ALOX15HIF1APTGS1KMT2A | |
| SCHEMBL16085123 | 0.86 | HIF1A (0.78) | CYP3A4ALOX15HIF1APTGS1KMT2A | |
| SCHEMBL1071994 | 0.85 | ALDH1A1 (0.52) | CYP3A4ALOX15HIF1APTGS1KMT2A | |
| SCHEMBL1067494 | 0.84 | CYP3A4 (0.51) | CYP3A4ALOX15HIF1APTGS1KMT2A | |
| SCHEMBL1069268 | 0.82 | CYP3A4 (0.49) | CYP3A4ALOX15HIF1APTGS1KMT2A | |
| SCHEMBL766080 | 0.81 | CYP3A4 (0.70) | CYP3A4ALOX15HIF1APTGS1KMT2A | |
| SCHEMBL14956630 | 0.81 | HIF1A (0.89) | CYP3A4ALOX15HIF1APTGS1KMT2A | |
| SCHEMBL5024973 | 0.81 | HIF1A (0.89) | CYP3A4ALOX15HIF1APTGS1KMT2A | |
| SCHEMBL29038261 | 0.79 | SMN1; SMN2 (0.62) | CYP3A4ALOX15HIF1APTGS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240074-A1 | Process Of Making Optically Pure Melphalan | PROVIDENT BANK | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240074-A1 | Process Of Making Optically Pure Melphalan | TYR, PAH, TET2 | CYP3A4 121/4885ALOX15 2166/4885HIF1A 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.