Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470063 | 0.83 | RGS4 (0.55) | KMT2AALDH1A1HSP90AA1SIGMAR1CA2 | |
| SCHEMBL1542663 | 0.79 | HSP90AA1 (0.71) | KMT2AALDH1A1HSP90AA1SIGMAR1CA2 | |
| SCHEMBL4854039 | 0.75 | NR1H3 (0.62) | KMT2AALDH1A1LMNATP53MAPT | |
| SCHEMBL4628903 | 0.74 | KMT2A (0.55) | KMT2AALDH1A1HSP90AA1SIGMAR1CA2 | |
| SCHEMBL10341825 | 0.74 | KMT2A (0.57) | KMT2AALDH1A1HSP90AA1SIGMAR1CA2 | |
| SCHEMBL8135497 | 0.72 | KMT2A (0.52) | KMT2AALDH1A1LDHAL3MBTL1 | |
| SCHEMBL16158991 | 0.72 | RGS4 (0.52) | KMT2AALDH1A1HSP90AA1LMNATP53 | |
| SCHEMBL17080644 | 0.72 | RGS4 (0.52) | KMT2AALDH1A1HSP90AA1LMNATP53 | |
| SCHEMBL30830857 | 0.72 | KMT2A (0.71) | KMT2AALDH1A1HSP90AA1SIGMAR1CA2 | |
| SCHEMBL13832415 | 0.72 | RGS4 (0.64) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233978-A1 | Novel 1-Aryl-3-Azabicyclo[3.1.0]Hexanes: Preparation And Use To Treat Neuropsychiatric Disorders | OTSUKA AMERICA PHARMACEUTICAL, INC. | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233978-A1 | Novel 1-Aryl-3-Azabicyclo[3.1.0]Hexanes: Preparation And Use To Treat Neuropsychiatric Disorders | HTR3C, HTR1B, HTR2C | KMT2A 998/4885ALDH1A1 176/4885HSP90AA1 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.