Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118149 | 0.84 | SMN1; SMN2 (0.50) | EGFRSMN1; SMN2POLBG6PDTLR9 | |
| SCHEMBL16857506 | 0.81 | EGFR (0.50) | EGFRSMN1; SMN2POLBG6PDTLR9 | |
| SCHEMBL12055674 | 0.77 | CRHBP (0.50) | EGFRSMN1; SMN2MAPTCRHBPCRHR2 | |
| SCHEMBL5115377 | 0.76 | PARP1 (0.51) | EGFRSMN1; SMN2POLBG6PDTLR9 | |
| SCHEMBL17037092 | 0.76 | MAPT (0.49) | EGFRSMN1; SMN2POLBG6PDTLR9 | |
| SCHEMBL11664475 | 0.76 | MAPT (0.51) | EGFRSMN1; SMN2POLBG6PDTLR9 | |
| Methane SCHEMBL27594830 | 0.75 | MAPT (0.50) | EGFRSMN1; SMN2POLBG6PDTLR9 | |
| SCHEMBL11714259 | 0.75 | HSPB1 (0.47) | SMN1; SMN2POLBG6PDTLR9MAPT | |
| SCHEMBL4208072 | 0.75 | PARP1 (0.57) | EGFRSMN1; SMN2POLBMAPTAHR | |
| SCHEMBL17037126 | 0.74 | CRHBP (0.47) | EGFRSMN1; SMN2MAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238768-A1 | MULTIMERIC MAGNETIC RESONANCE CONTRAST AGENTS | AXELSSON OSKAR | 2009-09-24 | — | — | US | disclosed |
| WO-2007064227-A1 | MULTIMERIC MAGENTIC RESONANCE CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238768-A1 | MULTIMERIC MAGNETIC RESONANCE CONTRAST AGENTS | MAG, MSR1, FABP7 | EGFR 3880/4885SMN1; SMN2 36/4885POLB 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.