Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324058 | 0.88 | TUBB4A (0.62) | KDM4EALDH1A1HPGDPOLBAPOBEC3A | |
| SCHEMBL15971349 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1HPGDPOLBAPOBEC3A | |
| SCHEMBL3144113 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1HPGDPOLBAPOBEC3A | |
| SCHEMBL14527151 | 0.85 | HTR2C (0.63) | KDM4EALDH1A1HPGDPOLBAPOBEC3A | |
| SCHEMBL3109875 | 0.85 | HDAC6 (0.61) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL1809488 | 0.84 | HDAC6 (0.51) | KDM4EALDH1A1HPGDPOLBAPOBEC3A | |
| SCHEMBL27945690 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1HPGDPOLBAPOBEC3A | |
| SCHEMBL6086357 | 0.84 | HDAC6 (0.65) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL30185511 | 0.84 | HDAC6 (0.67) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL30185500 | 0.84 | HDAC6 (0.78) | HDAC6HDAC8HDAC11HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | KDM4E 1604/4885ALDH1A1 4542/4885HPGD 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.