Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210658 | 0.82 | LMNA (0.49) | HTTSMN1; SMN2LTA4HALDH1A1TDP1 | |
| SCHEMBL2655449 | 0.81 | TEAD4 (0.47) | NPC1RAB9AHTTMAPTSMN1; SMN2 | |
| SCHEMBL3772542 | 0.81 | GAA (0.50) | NPC1RAB9AHTTMAPTSMN1; SMN2 | |
| SCHEMBL2667405 | 0.80 | CYP1A2 (0.46) | L3MBTL1 | |
| SCHEMBL21384250 | 0.80 | MAP4K4 (0.43) | MAPTMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL10329783 | 0.80 | ALDH1A1 (0.50) | NPC1RAB9AHTTMAPTALDH1A1 | |
| SCHEMBL184691 | 0.78 | ALDH1A1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL184686 | 0.78 | CYP19A1 (0.44) | NPC1RAB9AMAPTSMN1; SMN2MAOB | |
| SCHEMBL31510825 | 0.77 | KDM4E (0.42) | NPC1RAB9AMAPTLTA4HPIK3CA | |
| SCHEMBL2667220 | 0.76 | MAP4K4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662211-A1 | G PROTEIN-COUPLED RECEPTOR KINASE 2 (GRK2) DEGRADATION COMPOUNDS AND USE THEREOF | Nanjing Huanbo Biotechnology Co., Ltd. (CN) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024165075-A1 | G PROTEIN-COUPLED RECEPTOR KINASE 2 (GRK2) DEGRADATION COMPOUNDS AND USE THEREOF | NANJING HUANBO BIOTECHNOLOGY CO., LTD. (CN) | 2024-08-15 | — | — | WO | disclosed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | NPC1 2338/4885RAB9A 2492/4885HTT 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.