Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.57 |
| ▸ | PPARA | Q07869 | 17/20 | 0.57 |
| ▸ | PPARD | Q03181 | 15/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228991 | 0.91 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL12568368 | 0.85 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL12568367 | 0.85 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL12621106 | 0.85 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL2001979 | 0.81 | PPARA (0.52) | PPARGPPARAPPARD | |
| SCHEMBL12568369 | 0.79 | PPARA (0.57) | PPARGPPARAPPARD | |
| SCHEMBL8029435 | 0.78 | ATM (0.53) | — | |
| SCHEMBL12568378 | 0.77 | PPARA (0.59) | PPARGPPARAPPARD | |
| SCHEMBL4223705 | 0.76 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL2001889 | 0.74 | PPARD (0.51) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592361-B2 | (5-{3-[4-(4,5,6,7-tetrahydro-benzooxazol-2-yl)-phenoxy]-propoxy}-indol-1-yl)-acetic acid; diabetes, obesity, hyperlipidemia, and atherosclerotic disease | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |