Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.52 |
| ▸ | PPARD | Q03181 | 13/20 | 0.52 |
| ▸ | PPARG | P37231 | 18/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004565 | 0.85 | PPARG (0.55) | PPARAPPARDPPARG | |
| SCHEMBL4228991 | 0.84 | PPARG (0.69) | PPARAPPARDPPARG | |
| SCHEMBL13699062 | 0.81 | PPARG (0.57) | PPARAPPARDPPARG | |
| SCHEMBL12621106 | 0.79 | PPARG (0.51) | PPARAPPARDPPARG | |
| SCHEMBL2000809 | 0.79 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL2002211 | 0.78 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL1383087 | 0.78 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL1385875 | 0.78 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL1998775 | 0.77 | NPC1 (0.44) | PPARAPPARDPPARG | |
| SCHEMBL12568504 | 0.77 | PPARG (0.45) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964622-B2 | Indole acetic acid derivatives and their use as pharmaceutical agents | BAYER HEALTHCARE LLC (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090298854-A1 | Indole acetic acid derivatives and their use as pharmaceutical agents | MA XIN | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298854-A1 | Indole acetic acid derivatives and their use as pharmaceutical agents | IDO1, IDO2, AADAT | PPARA 243/4885PPARD 452/4885PPARG 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.