SCHEMBL13699172

SCHEMBL13699172

Oc1cccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)c1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 12/20 0.65
HSD17B2 P37059 11/20 0.65
CYP3A4 P08684 3/20 0.65
CYP2C9 P11712 3/20 0.65
ESR1 P03372 5/20 0.50
ESR2 Q92731 4/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2D6 P10635 2/20 0.50
CYP2B6 P20813 2/20 0.50
CYP2C19 P33261 2/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
ABL1 P00519 1/20 0.47
ABCB1 P08183 1/20 0.47
BCR P11274 1/20 0.47
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
CYP17A1 P05093 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23789706 1.00 HSD17B1 (0.65) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL22942255 0.96 HSD17B1 (0.68) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL2623450 0.94 HSD17B1 (0.74) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL2623461 0.92 HSD17B1 (0.54) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL9136317 0.92 HSD17B1 (0.54) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL23789713 0.92 HSD17B2 (0.55) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL504209 0.90 HSD17B1 (0.50) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL223856 0.90 HSD17B1 (0.50) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL913348 0.90 HSD17B1 (0.50) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL23789708 0.90 HSD17B2 (0.57) HSD17B1HSD17B2CYP3A4CYP2C9ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552208-B Fluorescent molecule for eye drop quality detection and preparation and application thereof 井冈山大学 2022-06-10 CN disclosed
CN-112552208-B Fluorescent molecule for eye drop quality detection and preparation and application thereof 井冈山大学 2022-06-10 CN disclosed
US-11029615-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-06-08 US disclosed
US-20210033991-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2021-02-04 US disclosed
EP-1672003-B1 Coating liquid and electrophotographic photoreceptor prepared using the coating liquid RICOH KK (JP) 2009-09-02 EP disclosed
EP-1174771-B1 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KK (JP) 2008-06-11 EP disclosed
EP-1857884-A1 Image forming apparatus and image forming method Ricoh Company, Ltd. (JP) 2007-11-21 EP disclosed