Sugi Predict

Sugi Predict / Compounds / SCHEMBL913348

SCHEMBL913348

SCHEMBL913348

Oc1cccc(N(c2ccccc2)c2ccc(-c3ccc(-c4ccc(N(c5ccccc5)c5cccc(O)c5)cc4)cc3)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B1 P14061 9/20 0.50
▸ HSD17B2 P37059 9/20 0.50
▸ CYP3A4 P08684 5/20 0.50
▸ ALDH1A1 P00352 4/20 0.50
▸ CYP2C9 P11712 2/20 0.50
▸ TSHR P16473 2/20 0.50
▸ KDM4E B2RXH2 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ MMP3 P08254 1/20 0.43
▸ BCL2L1 Q07817 1/20 0.43
▸ ESR1 P03372 3/20 0.42
▸ ESR2 Q92731 2/20 0.42
▸ CA12 O43570 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223856 1.00 HSD17B1 (0.50) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9
SCHEMBL504209 1.00 HSD17B1 (0.50) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9
SCHEMBL9136317 0.98 HSD17B1 (0.54) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9
Water SCHEMBL913259 0.98 CYP3A4 (0.48) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9
SCHEMBL2623461 0.98 HSD17B1 (0.54) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9
SCHEMBL13104514 0.96 HSD17B1 (0.53) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9
SCHEMBL3108730 0.96 HSD17B1 (0.54) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9
Bicarbonate SCHEMBL9000318 0.94 ALDH1A1 (0.46) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9
SCHEMBL8819150 0.94 ALDH1A1 (0.56) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9
SCHEMBL14617097 0.94 ALDH1A1 (0.56) HSD17B1HSD17B2CYP3A4ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799497-B2 Silanol containing overcoated photoconductors XEROX CORPORATION (US) 2010-09-21 — — US claimed
US-7592110-B2 Polyhydroxy siloxane photoconductors XEROX CORPORATION (US) 2009-09-22 — — US claimed
US-20090149675-A1 PROCESS FOR THE PREPARATION OF ARYL-DIAMINES XEROX CORPORATION (US) 2009-06-11 — — US claimed
US-7544842-B1 Process for the preparation of aryl-diamines XEROX CORPORATION (US) 2009-06-09 — — US claimed
US-20090131721-A1 METHOD OF DEPROTECTION OF ALKYL ARYLAMINE ETHERS XEROX CORPORATION (US) 2009-05-21 — — US claimed
US-20080193866-A1 Polyhydroxy siloxane photoconductors XEROX CORPORATION 2008-08-14 — — US claimed
US-20080107985-A1 Silanol containing overcoated photoconductors XEROX CORPORATION 2008-05-08 — — US claimed
US-9859505-B2 Charge-transporting molecular glass mixtures, luminescent molecular glass mixtures, or combinations thereof or organic light emitting diodes and other organic electronics and photonics applications MOLECULAR GLASSES, INC. (US) 2018-01-02 — — US disclosed
EP-2278405-B1 Methods of making a photoreceptor outer layer XEROX CORP (US) 2017-04-19 — — EP disclosed
EP-3039487-A1 MOLECULAR GLASS MIXTURES FOR ORGANIC ELECTRONICS APPLICATIONS Molaire Consulting LLC (US) 2016-07-06 — — EP disclosed
EP-2112557-B1 Imaging member and imaging apparatus using the same XEROX CORP (US) 2015-11-04 — — EP disclosed
US-9075325-B2 High speed charge transport layer XEROX CORPORATION (US) 2015-07-07 — — US disclosed
US-20150179714-A1 Crosslinkable, /Polymerizable and Combinations Thereof Charge-transporting Molecular Glass Mixtures, Luminescent Molecular Glass Mixtures, or Combinations Thereof for Organic Light Emitting Diodes and other Organic Electronics and Photonics Applications and Mothod of Making Same. Molaire Consulting 2015-06-25 — — US disclosed
US-5368967-A Layered photoreceptor with overcoat containing hydrogen bonded materials XEROX CORPORATION (US) 1994-11-29 — — US disclosed
EP-0295126-B1 ARYLAMINE-CONTAINING POLYHYDROXY ETHER RESINS XEROX CORPORATION (US) 1993-08-04 — — EP disclosed
EP-0295115-B1 ARYLAMINE COMPOUNDS XEROX CORPORATION (US) 1992-06-24 — — EP disclosed
US-5011939-A Hydroxy functionalized arylamine compounds XEROX CORPORATION (US) 1991-04-30 — — US disclosed
US-4956440-A Arylamine containing polyhydroxyether resins XEROX CORPORATION (US) 1990-09-11 — — US disclosed
US-4895783-A SOLVENT RESISTANCE, WEAR RESISTANCE XEROX CORPORATION (US) 1990-01-23 — — US disclosed
US-4818650-A Arylamine containing polyhydroxy ether resins and system utilizing arylamine containing polyhydroxyl ether resins XEROX CORPORATION (US) 1989-04-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149675-A1 PROCESS FOR THE PREPARATION OF ARYL-DIAMINES DDT, DDC, HDHD5 HSD17B1 610/4885HSD17B2 481/4885CYP3A4 87/4885
US-20090131721-A1 METHOD OF DEPROTECTION OF ALKYL ARYLAMINE ETHERS NAT1, PNMT, AADAC HSD17B1 450/4885HSD17B2 285/4885CYP3A4 79/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.