Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.45 |
| ▸ | HTR3B | O95264 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699142 | 0.85 | OPRK1 (0.54) | OPRK1SLC6A2SLC6A3HRH3HTR3E | |
| SCHEMBL1431606 | 0.81 | HRH3 (0.48) | OPRK1HRH3PTGS1PTGS2MEN1 | |
| SCHEMBL1431608 | 0.81 | HRH3 (0.48) | OPRK1HRH3PTGS1PTGS2MEN1 | |
| SCHEMBL16286908 | 0.81 | CHRM1 (0.49) | OPRK1SLC6A2SLC6A3HTR3EHTR3B | |
| SCHEMBL16286910 | 0.81 | CHRM1 (0.49) | OPRK1SLC6A2SLC6A3HTR3EHTR3B | |
| SCHEMBL4170072 | 0.79 | SLC6A3 (0.55) | OPRK1SLC6A2SLC6A3HTR3ACYP2D6 | |
| SCHEMBL1177444 | 0.79 | SLC6A3 (0.55) | OPRK1SLC6A2SLC6A3HTR3ACYP2D6 | |
| SCHEMBL1177443 | 0.79 | SLC6A3 (0.55) | OPRK1SLC6A2SLC6A3HTR3ACYP2D6 | |
| SCHEMBL4170069 | 0.79 | SLC6A3 (0.55) | OPRK1SLC6A2SLC6A3HTR3ACYP2D6 | |
| SCHEMBL4236560 | 0.78 | SLC6A2 (0.67) | OPRK1SLC6A2SLC6A3HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | OPRK1 124/4885SLC6A2 331/4885SLC6A3 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.