SCHEMBL13699191

SCHEMBL13699191

NCCCCCNC(=O)c1cccc(S(=O)(=O)OCCOCCNC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 3/20 0.46
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
RHOC P08134 3/20 0.44
RHOA P61586 3/20 0.44
TP53BP1 Q12888 1/20 0.43
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
CA2 P00918 3/20 0.40
GAA P10253 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13699232 0.90 CA2 (0.52) NAMPTHDAC3HDAC1RHOCRHOA
SCHEMBL13699283 0.88 TP53BP1 (0.45) NAMPTHDAC3HDAC1RHOCRHOA
SCHEMBL13699282 0.83 CA2 (0.48) NAMPTHDAC3HDAC1RHOCRHOA
SCHEMBL13699325 0.83 CA2 (0.48) NAMPTHDAC3HDAC1RHOCRHOA
SCHEMBL13699181 0.81 CA1 (0.45) NAMPTHDAC3HDAC1RHOCRHOA
SCHEMBL13699235 0.81 CA1 (0.45) NAMPTHDAC3HDAC1RHOCRHOA
SCHEMBL13699284 0.80 CA2 (0.50) NAMPTHDAC3HDAC1RHOCRHOA
SCHEMBL13699120 0.78 RHOC (0.58) NAMPTHDAC3HDAC1RHOCRHOA
SCHEMBL13699215 0.77 CA1 (0.47) NAMPTHDAC3HDAC1RHOCRHOA
SCHEMBL19133527 0.73 POLB (0.70) NAMPTHDAC3HDAC1TP53BP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009113704-A2 FLUORINE-CONTAINING COMPOUND AND METHOD FOR DETECTING BIOMOLECULE USING THE SAME KYOTO UNIVERSITY (JP) 2009-09-17 WO disclosed