Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 5/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 6/20 | 0.35 |
| ▸ | FGF1 | P05230 | 5/20 | 0.35 |
| ▸ | FGF2 | P09038 | 5/20 | 0.35 |
| ▸ | VEGFA | P15692 | 3/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975879 | 1.00 | GJB2 (0.47) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL15976025 | 0.89 | GJB2 (0.46) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL14418557 | 0.88 | GJB2 (0.44) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL15255429 | 0.88 | GJB2 (0.54) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL13699176 | 0.85 | GJB2 (0.41) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL15255405 | 0.84 | GJB2 (0.42) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL15255427 | 0.84 | GJB2 (0.42) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL10292101 | 0.84 | GJB2 (0.48) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL19204221 | 0.84 | GJB2 (0.48) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL15045693 | 0.83 | SSTR1 (0.46) | GJB2HPSEFGF1FGF2VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009112951-A2 | MUTANTS OF GLYCOSIDE HYDROLASES AND USES THEREOF FOR SYNTHESIZING COMPLEX OLIGOSACCHARIDES AND DISACCHARIDE INTERMEDIATES | INSTITUT PASTEUR (FR) | 2009-09-17 | — | — | WO | disclosed |
| EP-2100966-A1 | Mutants of glycoside hydrolases and uses thereof for synthesizing complex oligosaccharides and disaccharide intermediates | Institut Pasteur (FR) | 2009-09-16 | — | — | EP | disclosed |