Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 9/20 | 0.36 |
| ▸ | FGF1 | P05230 | 7/20 | 0.36 |
| ▸ | FGF2 | P09038 | 7/20 | 0.36 |
| ▸ | VEGFA | P15692 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | BMP2 | P12643 | 1/20 | 0.32 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.32 |
| ▸ | SHH | Q15465 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19731769 | 0.87 | GJB2 (0.43) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL15975926 | 0.86 | NT5E (0.40) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL14436853 | 0.86 | GJB2 (0.39) | GJB2BCHECYP2D6THRBHSD17B10 | |
| SCHEMBL18744561 | 0.86 | GJB2 (0.39) | GJB2BCHECYP2D6THRBHSD17B10 | |
| SCHEMBL13699219 | 0.85 | GJB2 (0.47) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL15975879 | 0.85 | GJB2 (0.47) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL14418557 | 0.85 | GJB2 (0.44) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL18315051 | 0.84 | GJB2 (0.46) | GJB2HPSEFGF1FGF2VEGFA | |
| SCHEMBL15975985 | 0.83 | ALDH1A1 (0.37) | BCHETHRBHSD17B10 | |
| SCHEMBL15975868 | 0.83 | ALDH1A1 (0.37) | BCHETHRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009112951-A2 | MUTANTS OF GLYCOSIDE HYDROLASES AND USES THEREOF FOR SYNTHESIZING COMPLEX OLIGOSACCHARIDES AND DISACCHARIDE INTERMEDIATES | INSTITUT PASTEUR (FR) | 2009-09-17 | — | — | WO | disclosed |
| EP-2100966-A1 | Mutants of glycoside hydrolases and uses thereof for synthesizing complex oligosaccharides and disaccharide intermediates | Institut Pasteur (FR) | 2009-09-16 | — | — | EP | disclosed |