Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699230 | 1.00 | TSHR (0.48) | TSHRATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL6069907 | 0.82 | TSHR (0.57) | TSHRATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL6069900 | 0.82 | TSHR (0.57) | TSHRATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL6069915 | 0.82 | TSHR (0.57) | TSHRATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL18166910 | 0.75 | TSHR (0.46) | TSHRL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL17577372 | 0.75 | TSHR (0.46) | TSHRL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL13302724 | 0.74 | ALDH1A1 (0.50) | TSHRL3MBTL1ALDH1A1KMT2ATDP1 | |
| SCHEMBL20253755 | 0.74 | ALDH1A1 (0.50) | TSHRL3MBTL1ALDH1A1KMT2ATDP1 | |
| SCHEMBL13302678 | 0.74 | ALDH1A1 (0.50) | TSHRL3MBTL1ALDH1A1KMT2ATDP1 | |
| SCHEMBL22958521 | 0.74 | TDP1 (0.41) | TSHRL3MBTL1ALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582797-B2 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfonates) and compositions comprising the same | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7582797-B2 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfonates) and compositions comprising the same | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-09-01 | — | — | US | disclosed |