Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069900 | 1.00 | TSHR (0.57) | TSHRATMCYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL6069915 | 1.00 | TSHR (0.57) | TSHRATMCYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL13699230 | 0.82 | TSHR (0.48) | TSHRATMCYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL13699311 | 0.82 | TSHR (0.48) | TSHRATMCYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL6069567 | 0.79 | FASN (0.47) | SMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL6069576 | 0.79 | FASN (0.47) | SMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL6817041 | 0.79 | FASN (0.47) | SMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL4604644 | 0.79 | FASN (0.47) | SMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL10028440 | 0.76 | CYP3A4 (0.46) | TSHRCYP3A4CYP2C19ALDH1A1POLB | |
| SCHEMBL13046117 | 0.76 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894346-A | Method for preparing aryl ketone compound and intermediate | 四川奥兰多化工有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-7056947-B2 | For inhibiting (cysteine) proteases/caspases; for treatment of viral infections, stroke, neurodegenerative disease, and inflammatory diseases | GEORGIA TECH RESEARCH CORP. (US) | 2006-06-06 | — | — | US | disclosed |
| US-20040048327-A1 | Aza-peptide epoxides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-03-11 | — | — | US | disclosed |
| WO-2004005270-A1 | AZA-PEPTIDE EPOXIDES | GEORGIA TECH RESEARCH CORPORATION (US) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048327-A1 | Aza-peptide epoxides | ANPEP, ENPEP, TMPRSS15 | TSHR 4503/4885ATM 4861/4885CYP3A4 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.