Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296855 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ATMTDP1ALOX5TSHR | |
| SCHEMBL13699389 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ATMTDP1ALOX5TSHR | |
| SCHEMBL8297217 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ATMTDP1ALOX5TSHR | |
| SCHEMBL25894404 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ATMTDP1ALOX5TSHR | |
| SCHEMBL13513384 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ATMTDP1ALOX5TSHR | |
| SCHEMBL25894118 | 0.88 | ALDH1A1 (0.42) | L3MBTL1ATMALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25894165 | 0.86 | CYP4F2 (0.40) | L3MBTL1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25894409 | 0.86 | MEN1 (0.44) | ALOX5TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL25894441 | 0.86 | CYP4F2 (0.40) | L3MBTL1ATMTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25894343 | 0.85 | KMT2A (0.50) | L3MBTL1ALOX5TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582797-B2 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfonates) and compositions comprising the same | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7582797-B2 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfonates) and compositions comprising the same | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-09-01 | — | — | US | disclosed |