Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16329905 | 0.87 | POLB (0.42) | BPTFALDH1A1TSHRP2RX7HSD11B1 | |
| SCHEMBL13538409 | 0.75 | P2RX7 (0.40) | ALDH1A1P2RX7EPHX2HSD11B1 | |
| SCHEMBL5327206 | 0.75 | ALDH1A1 (0.41) | BPTFALDH1A1TSHRHSD11B1 | |
| SCHEMBL1074062 | 0.73 | ALDH1A1 (0.57) | BPTFALDH1A1TSHRP2RX7EPHX2 | |
| SCHEMBL25909650 | 0.73 | ALDH1A1 (0.57) | BPTFALDH1A1TSHRP2RX7EPHX2 | |
| SCHEMBL3716616 | 0.72 | ALDH1A1 (0.38) | BPTFALDH1A1TSHRP2RX7EPHX2 | |
| SCHEMBL25245007 | 0.71 | — | — | |
| SCHEMBL10820607 | 0.68 | POLB (0.44) | BPTFALDH1A1TSHRP2RX7HSD11B1 | |
| SCHEMBL1594749 | 0.68 | ALDH1A1 (0.32) | BPTFALDH1A1GAA | |
| SCHEMBL19174061 | 0.67 | ALDH1A1 (0.50) | BPTFALDH1A1TSHRP2RX7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106564-A2 | IMAGING THE CENTRAL NERVOUS SYSTEM | GE HEALTHCARE LIMITED (GB) | 2009-09-03 | — | — | WO | disclosed |