Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673004 | 0.92 | IL1B (0.42) | IL1BP2RX7 | |
| SCHEMBL1019418 | 0.88 | IL1B (0.42) | IL1BP2RX7 | |
| SCHEMBL1020688 | 0.88 | IL1B (0.55) | IL1BP2RX7 | |
| SCHEMBL13672960 | 0.87 | IL1B (0.39) | IL1BP2RX7 | |
| SCHEMBL12955288 | 0.84 | IL1B (0.42) | IL1BP2RX7 | |
| SCHEMBL12955184 | 0.83 | P2RX7 (0.44) | IL1BP2RX7 | |
| SCHEMBL11955064 | 0.82 | IL1B (0.44) | IL1BP2RX7 | |
| SCHEMBL11954264 | 0.81 | P2RX7 (0.46) | IL1BP2RX7 | |
| SCHEMBL12955035 | 0.81 | IL1B (0.51) | IL1BP2RX7 | |
| SCHEMBL13673005 | 0.81 | IL1B (0.42) | IL1BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105164-A1 | Novel P2X7R antagonists and their use | Affectis Pharmaceuticals AG (DE) | 2009-09-30 | — | — | EP | disclosed |