Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 16/20 | 0.41 |
| ▸ | IL1B | P01584 | 12/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673135 | 0.90 | P2RX7 (0.40) | P2RX7IL1BCNR2CNR1 | |
| SCHEMBL13699794 | 0.89 | CNR2 (0.38) | P2RX7IL1BCNR2CNR1 | |
| SCHEMBL1019591 | 0.88 | P2RX7 (0.41) | P2RX7IL1BCNR2CNR1 | |
| SCHEMBL13673133 | 0.88 | P2RX7 (0.39) | P2RX7IL1B | |
| SCHEMBL1020305 | 0.88 | P2RX7 (0.44) | P2RX7IL1B | |
| SCHEMBL1020804 | 0.88 | P2RX7 (0.41) | P2RX7IL1BCNR2CNR1 | |
| SCHEMBL13672991 | 0.87 | CNR2 (0.35) | P2RX7IL1BCNR2 | |
| SCHEMBL13673074 | 0.84 | P2RX7 (0.50) | P2RX7IL1B | |
| SCHEMBL13699802 | 0.82 | CNR2 (0.39) | P2RX7IL1BCNR2CNR1 | |
| SCHEMBL13672994 | 0.82 | P2RX7 (0.42) | P2RX7IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105164-A1 | Novel P2X7R antagonists and their use | Affectis Pharmaceuticals AG (DE) | 2009-09-30 | — | — | EP | disclosed |