Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12955308 | 0.92 | P2RX7 (0.40) | P2RX7IL1B | |
| SCHEMBL1019588 | 0.91 | P2RX7 (0.41) | P2RX7IL1B | |
| SCHEMBL1020260 | 0.91 | P2RX7 (0.39) | P2RX7IL1B | |
| SCHEMBL1020683 | 0.91 | P2RX7 (0.51) | P2RX7IL1B | |
| SCHEMBL13673074 | 0.84 | P2RX7 (0.50) | P2RX7IL1B | |
| SCHEMBL11954264 | 0.83 | P2RX7 (0.46) | P2RX7IL1B | |
| SCHEMBL13673003 | 0.83 | P2RX7 (0.49) | P2RX7IL1B | |
| SCHEMBL12954990 | 0.82 | P2RX7 (0.44) | P2RX7IL1B | |
| SCHEMBL12955184 | 0.81 | P2RX7 (0.44) | P2RX7IL1B | |
| SCHEMBL11955064 | 0.78 | IL1B (0.44) | P2RX7IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105164-A1 | Novel P2X7R antagonists and their use | Affectis Pharmaceuticals AG (DE) | 2009-09-30 | — | — | EP | disclosed |