SCHEMBL13699891

SCHEMBL13699891

Cc1c(-c2ccc([SH](C)(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)cccc1C(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
PPARA Q07869 2/20 0.34
PPARG P37231 1/20 0.34
USP1 O94782 3/20 0.34
WDR48 Q8TAF3 3/20 0.34
GABRA1 P14867 3/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRB2 P47870 2/20 0.32
TSHR P16473 2/20 0.32
FAAH O00519 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6318808 0.83 PDCD1 (0.50) CA1CA2CA12CA9PDCD1
SCHEMBL13821976 0.80 CD274 (0.41) CA1CA2CA12CA9PDCD1
SCHEMBL10304823 0.76 CA1 (0.40) CA1CA2CA12CA9PDCD1
SCHEMBL13366135 0.75 CD274 (0.51) PDCD1CD274PPARAPPARGPTGS1
SCHEMBL12648686 0.75 CA1 (0.40) CA1CA2CA12CA9PDCD1
SCHEMBL10304798 0.74 GABRA1 (0.50) CA1CA2CA12CA9PPARA
SCHEMBL12648768 0.72 CA1 (0.38) CA1CA2CA12CA9GABRA1
SCHEMBL13366078 0.72 ABL1 (0.47) PDCD1CD274PPARAPPARGTSHR
SCHEMBL13760021 0.72 RXRA (0.32) CA1CA2GABRA1GABRB2GABRB1
SCHEMBL8680514 0.72 GABRA1 (0.44) CA1CA2CA12CA9USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2098532-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-09-09 EP disclosed
EP-2085450-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-08-05 EP disclosed