SCHEMBL13700186

SCHEMBL13700186

C[Si](C)(C)CCCNC(=O)c1ccccc1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NAAA Q02083 1/20 0.68
▸ HTT P42858 3/20 0.63
▸ TSHR P16473 2/20 0.63
▸ HPGD P15428 2/20 0.63
▸ NPC1 O15118 1/20 0.63
▸ ALDH1A1 P00352 1/20 0.63
▸ MAPT P10636 1/20 0.63
▸ NPSR1 Q6W5P4 1/20 0.63
▸ HSD17B10 Q99714 1/20 0.63
▸ NLRP1 Q9C000 1/20 0.63
▸ ALOX5 P09917 3/20 0.57
▸ NAMPT P43490 1/20 0.53
▸ MEN1 O00255 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ POLB P06746 1/20 0.52
▸ ESRRG P62508 1/20 0.52
▸ HDAC7 Q8WUI4 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.49
▸ MPO P05164 1/20 0.49
▸ GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16404658 0.85 NAAA (0.61) NAAAHTTTSHRHPGDNPC1
Hydrochloric Acid SCHEMBL15769552 0.84 HTT (0.73) NAAAHTTTSHRHPGDNPC1
SCHEMBL823552 0.84 NAAA (0.84) NAAAHTTTSHRHPGDNPC1
SCHEMBL3148607 0.83 NAAA (0.88) NAAAHTTTSHRHPGDNPC1
SCHEMBL31119120 0.82 HTT (0.69) NAAAHTTTSHRHPGDNPC1
SCHEMBL5707054 0.82 HTT (0.69) NAAAHTTTSHRHPGDNPC1
SCHEMBL31119121 0.82 HTT (0.69) NAAAHTTTSHRHPGDNPC1
SCHEMBL1754795 0.82 NAAA (0.69) NAAAHTTTSHRHPGDNPC1
SCHEMBL1648484 0.82 NAAA (0.97) NAAAHTTTSHRHPGDNPC1
SCHEMBL8980556 0.81 HTT (0.69) NAAAHTTTSHRHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8586692-B2 Light protective additive based on organic/inorganic hybrid polymer, method for its manufacture and use thereof NOR-X INDUSTRY AS (NO) 2013-11-19 — — US disclosed
US-20090234147-A1 Light Protective Additive Based on Organic/Inorganic Hybrid Polymer, Method for Its Manufacture and Use thereof Funzionano AS (NO) 2009-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090234147-A1 Light Protective Additive Based on Organic/Inorganic Hybrid Polymer, Method for Its Manufacture and Use thereof RAD51, C9, H1-4 NAAA 2843/4885HTT 1876/4885TSHR 2257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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