⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597929 | 0.76 | — | — | |
| Mechlorethamine SCHEMBL11905424 | 0.69 | MAPT (1.00) | — | |
| SCHEMBL9813047 | 0.69 | — | — | |
| Mechlorethamine SCHEMBL3861 | 0.69 | — | — | |
| SCHEMBL131951 | 0.69 | — | — | |
| SCHEMBL29262141 | 0.67 | — | — | |
| Mechlorethamine SCHEMBL3855 | 0.67 | — | — | |
| Mechlorethamine SCHEMBL10618376 | 0.67 | LMNA (1.00) | — | |
| Mechlorethamine SCHEMBL2554459 | 0.67 | — | — | |
| Mechlorethamine SCHEMBL5330778 | 0.67 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395997-B1 | TREATING INFLAMMATION AND INFLAMMATORY PAIN IN MUCOSA USING MUCOSAL PROLONGED RELEASE BIOADHESIVE THERAPEUTIC CARRIERS. | ONXEO S A (FR) | 2016-02-10 | — | — | EP | disclosed |
| US-9192599-B2 | Treating inflammation and inflammatory pain in mucosa using mucosal prolonged release bioadhesive therapeutic carriers | ONXEO S.A. (FR) | 2015-11-24 | — | — | US | disclosed |
| US-9089559-B2 | Treating inflammation and inflammatory pain in mucosa using mucosal prolonged release bioadhesive therapeutic carriers | ONXEO S.A. (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20130274306-A1 | TREATING INFLAMMATION AND INFLAMMATORY PAIN IN MUCOSA USING MUCOSAL PROLONGED RELEASE BIOADHESIVE THERAPEUTIC CARRIERS | Monopar Therapeutics Inc. | 2013-10-17 | — | — | US | disclosed |
| US-20110288140-A1 | TREATING INFLAMMATION AND INFLAMMATORY PAIN IN MUCOSA USING MUCOSAL PROLONGED RELEASE BIOADHESIVE THERAPEUTIC CARRIERS | BIOALLIANCE PHARMA ,S.A. (FR) | 2011-11-24 | — | — | US | disclosed |
| EP-2368549-A1 | Treating hand-foot syndrome and related pathologies using clonidine or its derivatives | BioAlliance Pharma (FR) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010031819-A1 | TREATING INFLAMMATION AND INFLAMMATORY PAIN IN MUCOSA USING MUCOSAL PROLONGED RELEASE BIOADHESIVE THERAPEUTIC CARRIERS. | BIOALLIANCE PHARMA (FR) | 2010-03-25 | — | — | WO | disclosed |
| EP-2165706-A1 | Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers. | BioAlliance Pharma (FR) | 2010-03-24 | — | — | EP | disclosed |