⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mechlorethamine SCHEMBL11905424 | 1.00 | MAPT (1.00) | — | |
| Mechlorethamine SCHEMBL3855 | 0.96 | — | — | |
| Mechlorethamine SCHEMBL2554459 | 0.96 | — | — | |
| Mechlorethamine SCHEMBL5330778 | 0.96 | LMNA (1.00) | — | |
| Mechlorethamine SCHEMBL10618376 | 0.96 | LMNA (1.00) | — | |
| Mechlorethamine SCHEMBL15532070 | 0.93 | — | — | |
| Mechlorethamine SCHEMBL9139106 | 0.93 | LMNA (0.93) | — | |
| Mechlorethamine SCHEMBL12802922 | 0.93 | MAPT (0.86) | — | |
| Mechlorethamine SCHEMBL23909362 | 0.89 | MAPT (0.80) | — | |
| SCHEMBL14708803 | 0.87 | MAPT (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 149646 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4748859-A2 | CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF | The Regents of the University of California (US) | 2026-05-27 | — | — | EP | claimed |
| CN-116209439-B | Cereblon protein modulators | Saint Jude Children's Research Hospital Ltd. (US) | 2026-05-26 | — | — | CN | claimed |
| US-20260137678-A1 | METHODS FOR TREATING OR PREVENTING NEUROENDOCRINE TUMOR FORMATION USING XPO1 INHIBITORS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2026-05-21 | — | — | US | claimed |
| WO-2026107377-A1 | PHARMACOLOGICAL RE-ACTIVATION OF MUTANT PVHL | KARANICOLAS JOHN (US) | 2026-05-21 | — | — | WO | claimed |
| US-20260139071-A1 | Subcutaneous Formulations Of Anti-CD38 Antibodies And Their Uses | JANSSEN BIOTECH INC (US) | 2026-05-21 | — | — | US | claimed |
| US-20260137650-A1 | MODULATORS OF RAR RELATED ORPHAN RECEPTORS (RORs) | 11949098 CANADA INC (CA) | 2026-05-21 | — | — | US | claimed |
| US-20260137794-A1 | LIGAND-DRUG CONJUGATE AND USE THEREOF | SYSTIMMUNE INC (US) | 2026-05-21 | — | — | US | claimed |
| US-20260137700-A1 | PHARMACEUTICAL COMBINATION OF PRMT5 INHIBITOR AND DNA DAMAGE-INDUCING SUBSTANCE | SK BIOPHARMACEUTICALS CO LTD (KR) | 2026-05-21 | — | — | US | claimed |
| WO-2026105121-A1 | ANTICANCER FORMULATIONS AND USES THEREOF | INTRAGEL THERAPEUTICS LTD. (IL) | 2026-05-21 | — | — | WO | claimed |
| EP-4743490-A1 | HUMANIZED ANTI-CD7 ANTIBODY | Christian-Albrechts-Universität zu Kiel (DE) | 2026-05-20 | — | — | EP | claimed |
| EP-0178743-A2 | Novel tritium labelled N-mustard type compounds and a process for their production | UNIVERSITY OF PITTSBURGH (US) | 1986-04-23 | — | — | EP | claimed |
| US-4584136-A | Process for preparing Estracyt compounds having a carcinostatic bound thereto | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) | 1986-04-22 | — | — | US | claimed |
| US-4569836-A | Cancer treatment by intracellular hyperthermia | GORDON, DAVID, SKOKIE, ILLINOIS | 1986-02-11 | — | — | US | claimed |
| US-4565806-A | Composition and method for rational treatment of cancer | SETAELAE KAI M E | 1986-01-21 | — | — | US | claimed |
| EP-0083600-A1 | Use of alkaloid derivatives for the manufacture of a medicament for the strengthening of the immune system and for the treatment of viral, bacterial and fungal infections. | NOWICKY WASSILI | 1983-07-20 | — | — | EP | claimed |
| WO-1983000486-A1 | METHOD FOR THE DIAGNOSTIC AND THE THERAPEUTIC TREATMENT OF TUMORS AND/OR INFECTIOUS DISEASES OF ALL SORTS BY THE USE OF ALKALOID COMPOSITIONS OR THE SALTS THEREOF | NOWICKY, WASSYL | 1983-02-17 | — | — | WO | claimed |
| US-4120754-A | SULFUR AND NITROGEN MUSTARD GASES; ADSORBING STRIP CONTAINING SILVER SALT OF A THIOPHOSPHORIC ACID, CHOLINESTERASE, CHROMOGEN | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TEN BEHOEVE VAN DE RIJKSVERDEDIGING (NL) | 1978-10-17 | — | — | US | claimed |
| US-4106488-A | Cancer treatment method | GORDON, DAVID, SKOKIE, ILLINOIS | 1978-08-15 | — | — | US | claimed |
| US-4083692-A | Detection and estimation of microquantities of alkylating agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1978-04-11 | — | — | US | claimed |
| US-4039484-A | Process for the production of anion-exchangeable nonhollow novolak filaments | KANEBO, LTD. (JA) | 1977-08-02 | — | — | US | claimed |