Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24770936 | 0.86 | CA1 (0.42) | CYP2C19HSD17B10KMT2ASMN1; SMN2CA1 | |
| SCHEMBL15726352 | 0.82 | TDP1 (0.41) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL19441166 | 0.82 | GAA (0.39) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL14616914 | 0.80 | ALDH1A1 (0.48) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL7876820 | 0.80 | GAA (0.38) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL19241801 | 0.78 | MGAM (0.37) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL4639637 | 0.77 | GABRR1 (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL13700412 | 0.77 | GABRR1 (0.54) | CYP2C19KMT2AMEN1 | |
| SCHEMBL7879761 | 0.77 | GABRR1 (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8847925 | 0.77 | CHRM1 (0.36) | GAACYP3A4CYP2C19TRPM8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623366-B1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | KOREA RES INST CHEMICAL TECH (KR) | 2022-01-19 | — | — | EP | disclosed |