Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699488 | 0.90 | CA2 (0.38) | MAPTALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL13700485 | 0.90 | MAPT (0.38) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL13700483 | 0.88 | MEN1 (0.39) | MAPTALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL13700470 | 0.88 | MAPT (0.46) | MAPTALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL13700480 | 0.88 | CA1 (0.43) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL13700475 | 0.86 | KDM4E (0.40) | MAPTALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL13700481 | 0.85 | GAA (0.44) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL13700535 | 0.84 | MAPT (0.42) | MAPTALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL13699437 | 0.83 | MAPT (0.46) | MAPTALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL14137967 | 0.83 | NPSR1 (0.38) | MAPTALDH1A1HPGDPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |