SCHEMBL13699437

SCHEMBL13699437

Cc1cc(CCO)cc(-n2nc3ccc(C(=O)Nc4ccccc4)cc3n2)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.46
ALDH1A1 P00352 7/20 0.46
HPGD P15428 4/20 0.46
POLB P06746 4/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
KDM4E B2RXH2 6/20 0.45
LMNA P02545 2/20 0.45
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
THRB P10828 1/20 0.41
HSD17B10 Q99714 4/20 0.41
MAPK1 P28482 3/20 0.41
TSHR P16473 2/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ESR1 P03372 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LCK P06239 2/20 0.40
AURKA O14965 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700445 0.87 LMNA (0.45) MAPTALDH1A1HPGDPOLBRAB9A
SCHEMBL13700466 0.87 ALDH1A1 (0.44) MAPTALDH1A1HPGDPOLBRAB9A
SCHEMBL13700470 0.87 MAPT (0.46) MAPTALDH1A1HPGDPOLBRAB9A
SCHEMBL13699440 0.86 ALDH1A1 (0.39) MAPTALDH1A1HPGDPOLBRAB9A
SCHEMBL13700414 0.86 MAPT (0.38) MAPTALDH1A1HPGDKDM4ELMNA
SCHEMBL13699503 0.85 ALDH1A1 (0.44) MAPTALDH1A1HPGDPOLBRAB9A
SCHEMBL13700405 0.85 ALDH1A1 (0.49) MAPTALDH1A1HPGDPOLBRAB9A
SCHEMBL13700411 0.83 CYP4A11 (0.44) MAPTALDH1A1HPGDPOLBRAB9A
SCHEMBL13700486 0.83 MAPT (0.42) MAPTALDH1A1HPGDPOLBRAB9A
SCHEMBL13700535 0.83 MAPT (0.42) MAPTALDH1A1HPGDPOLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed