SCHEMBL13701044

SCHEMBL13701044

O=C(c1ccc(C(=O)c2ccc(-c3nc4ccccc4c(=O)o3)s2)cc1)c1ccc(-c2nc3ccccc3c(=O)o2)s1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
KMT2A Q03164 3/20 0.54
F2 P00734 3/20 0.54
HPGD P15428 2/20 0.54
MEN1 O00255 2/20 0.54
ELANE P08246 2/20 0.51
TP53 P04637 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
HSD17B10 Q99714 1/20 0.47
C1R P00736 6/20 0.46
KDM4E B2RXH2 5/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
PLG P00747 1/20 0.46
KLK1 P06870 1/20 0.46
PRSS1 P07477 1/20 0.46
C1S P09871 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13701131 0.92 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2KMT2AF2HPGD
SCHEMBL13700956 0.91 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2KMT2AF2HPGD
SCHEMBL13701105 0.88 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2KMT2AF2HPGD
SCHEMBL2544499 0.83 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2KMT2AF2HPGD
SCHEMBL13701129 0.82 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2KMT2AF2HPGD
SCHEMBL13701134 0.78 ELANE (0.64) ALDH1A1SMN1; SMN2KMT2AF2HPGD
SCHEMBL29444205 0.77 ELANE (0.71) ALDH1A1SMN1; SMN2KMT2AF2HPGD
SCHEMBL692194 0.77 ELANE (0.71) ALDH1A1SMN1; SMN2KMT2AF2HPGD
SCHEMBL13701063 0.76 ELANE (0.50) ALDH1A1SMN1; SMN2KMT2AF2HPGD
SCHEMBL272287 0.73 ELANE (0.81) ALDH1A1SMN1; SMN2KMT2AF2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound CYP2A6, CYP2B6, XPO6 ALDH1A1 1360/4885SMN1; SMN2 4233/4885KMT2A 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.