Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701396 | 1.00 | TSHR (0.39) | TSHRALDH1A1TDP1SMN1; SMN2CYP2D6 | |
| SCHEMBL13701408 | 0.99 | TSHR (0.40) | TSHRALDH1A1TDP1SMN1; SMN2CYP2D6 | |
| SCHEMBL24775081 | 0.94 | TSHR (0.41) | TSHRALDH1A1TDP1SMN1; SMN2CYP2D6 | |
| SCHEMBL4263589 | 0.88 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1SMN1; SMN2S1PR1 | |
| SCHEMBL4269346 | 0.88 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1SMN1; SMN2S1PR1 | |
| SCHEMBL4257286 | 0.88 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1SMN1; SMN2S1PR1 | |
| SCHEMBL5895138 | 0.88 | TSHR (0.38) | TSHRALDH1A1TDP1SMN1; SMN2CYP2D6 | |
| SCHEMBL4258515 | 0.88 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1SMN1; SMN2S1PR1 | |
| SCHEMBL29829574 | 0.88 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1SMN1; SMN2S1PR1 | |
| SCHEMBL4263623 | 0.86 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585983-B2 | Alkylenedioxythiophenes and poly(alkylenedioxythiophenes) containing mesogenic groups | H.C. STARCK, GMBH (DE) | 2009-09-08 | — | — | US | disclosed |
| US-7585983-B2 | Alkylenedioxythiophenes and poly(alkylenedioxythiophenes) containing mesogenic groups | H.C. STARCK, GMBH (DE) | 2009-09-08 | — | — | US | disclosed |